Note, content for veterinary professionals only.

ANXITANE® (L-Theanine) Chewable Tablets

Relaxation inspired by nature

Helps dogs and cats that exhibit mild to moderate anxiety due to environmentally induced stress

  • Contains L-theanine, an amino acid present in green tea that promotes relaxation without causing drowsiness2
    • Open field trials showed ANXITANE® (L-Theanine) Chewable Tablets to be an effective solution for environmentally induced stress in dogs and cats8,9
  • In 4 published studies ANXITANE Chewable Tablets administration produced significant reductions in anxiety scores in cats and dogs

  • Palatable: about 94% of dogs and cats accepted ANXITANE Chewable Tablets in open field trials thanks to the umami (savory) taste of the L-theanine as well as the chicken flavoring of the chewable tablet1
  • Can be used daily or as needed when the dog/cat is exposed to stressful situations
  • 2 sizes of chewable tablets for dogs and cats: 
    • 50mg
    • 100mg

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  • ANXITANE (L-Theanine) Chewable Tablets can be useful to help manage dogs with storm sensitivity10

 

References:

1. Data on file. Virbac Corporation.

2. Nobre AC, Anling R, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. 2008;17(suppl 1):167–168.
3. Nathan PJ, Lu K, Gray M. The neuropharmacology of L-theanine (N-Ethyl-L-Glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006;6(2):21–30.

4. Kakuda T, Nozawa A, Sugimoto A, Niino H. Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors. Biosci Biotechnol Biochem. 2002;66:2683–2686.

5. Kakuda T. Neuroprotective effects of the green tea components theanine and catechins. Biol Pharm Bull. 2002;25:1513–1518.

6. Sugiyama T, Sadzuka Y. Theanine and glutamate transport inhibitors enhance the antitumor efficacy of chemotherapeutic agents. Biochim Biophys Acta. 2003;1653:47–59.

7. Yokogosi H, Kobayashi M, Mochizuki M, Terashima T. Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem Res. 1998;23:667–673.

8. Kern L. La transmission de la peur. In: Beata C, ed. La Communication. Collection Zoopsychiatrie. Marseille, France: Solal Editeurs; 2005:191–196.

9. Dramard V, Kern L, Hofmans J, Halsberghe C, Rème CA. Clinical efficacy of L-theanine tablets to reduce anxiety-related emotional disorders in cats: a pilot open-label clinical trial. J Vet Behav. 2007;2:85–86.

10. Pike AL, Horwitz DF, Lobprise H. An open-label prospective study of the use of L-theanine (Anxitane) in storm-sensitive client-owned dogs. J Vet Behav. 2015;10:324–331. 

 

Ingredients:

ACTIVE INGREDIENTS: ANXITANE® (L-Theanine) Chewable Tablets (S) 50 mg of L-Theanine (Suntheanine®), ANXITANE® (L-Theanine) Chewable Tablets (M/L) 100 mg of L-Theanine (Suntheanine®)
INACTIVE INGREDIENTS: Colloidal silica, magnesium stearate, microcrystalline cellulose, Pharmaburst® B1, polyvinylpolypyrrolidone, poultry flavor.