IMPORTANT SAFETY INFORMATION

TULISSIN^® 100 (tulathromycin injection):  Not for use in humans. Ensure a pre-slaughter withdrawal time of eighteen (18) days in cattle and five (5) days in swine.  Do not use in dairy cattle 20 months of age or older, including dry dairy cows.  Use in these cattle may cause drug residues in milk and/or in calves born to these cows.  The effects of tulathromycin on bovine and swine reproductive performance, pregnancy and lactation have not been determined.  Do not use in animals known to be hypersensitive to the product.

IMPORTANT SAFETY INFORMATION

TULISSIN^® 25 (tulathromycin injection):  Not for use in ruminating cattle.  Ensure a pre-slaughter withdrawal time of twenty-two (22) days in calves and five (5) days in swine.  The effects of tulathromycin on bovine and swine reproductive performance, pregnancy and lactation have not been determined.  Do not use in animals known to be hypersensitive to the product. 

SWINE IMPORTANT SAFETY INFORMATION

Tenotryl™ (enrofloxacin) 100 mg/ml Antimicrobial Injectable Solution:  Not for use in humans.  For intramuscular or subcutaneous use in swine.  Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian and prohibits the extra-label use of this drug in food producing animals. To assure responsible antimicrobial drug use, enrofloxacin should only be used as a second-line drug for colibacillosis in swine following consideration of other therapeutic options.  Animals intended for human consumption must not be slaughtered within 5 days of receiving a single injection dose. The effects of enrofloxacin on swine reproductive performance, pregnancy and lactation have not been adequately determined.   The long-term effects on articular joint cartilage have not been determined in pigs above market weight.  Subcutaneous or intramuscular injection in swine can cause a transient local tissue reaction and may result in trim loss of edible tissue at slaughter.  Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System (CNS) disorders. 

CATTLE IMPORTANT SAFETY INFORMATION

Tenotryl™ (enrofloxacin) 100 mg/ml Antimicrobial Injectable Solution:  Not for use in humans.  For subcutaneous use in beef cattle and non-lactating dairy cattle.  Not for use in female dairy cattle 20 months of age or older or in calves to be processed for veal. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian and prohibits the extra-label use of this drug in food producing animals. Animals intended for human consumption must not be slaughtered within 28 days from the last treatment. This product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows.  Use in these cattle may cause drug residues in milk and/or in the calves born to these cows.  A withdrawal period has not been established for this product in pre-ruminating calves.  The effects of enrofloxicin on cattle reproductive performance, pregnancy and lactation have not been adequately determined.  Do not exceed a 20 mL dose per injection site.  Subcutaneous injection in cattle can cause a transient local tissue reaction and may result in trim loss of edible tissue at slaughter.  Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System (CNS) disorders. 

IMPORTANT SAFETY INFORMATION

TIA™ 12.5% (tiamulin hydrogen fumarate) liquid concentrate:  Not for use in humans - for use in drinking water of swine only. Withdraw medicated water 3 days before slaughter after treatment at 3.5mg per pound body weight and 7 days before slaughter after treatment at 10.5mg per pound body weight. Prepare fresh medicated water daily. Use as the only source of drinking water for 5 days. Do not use undiluted. The effects of tiamulin on swine reproductive performance, pregnancy and lactation have not been determined. Swine being treated with TIA 12.5% liquid concentrate should not have access to feeds containing polyether ionophores (e.g., monensin, lasalocid, narasin, salinomycin and semduramicin) as adverse reactions may occur.  In rare cases, redness of the skin primarily over the ham and underline has been observed during medication.  If these signs appear, discontinue use of this drug.